When QTP is open am not able to open my AUT.

I have a desktop application, on running that Application after giving username and Password, it makes connection with backend.
Now, when QTP is close and i am opening my Application its working fine. But when i open QTP and add new test and than opening my Application it says connection refused. Same happen when i run my application using SystemUtil.Run.

Do i need to do any setting in QTP so, that my Application will work fine.

Please Help...

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